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Sadeghi A, Hami J, Razavi S, Esfandiary E, Hejazi Z

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doi: 10.3389/fmed.2021.651552 13 MaTLZhouYWangCWangLChenJXYangHHet al

The inflammatory link between psoriasis and systemic health is underscored by reduced lifespan among those afflicted with this disease: moderate-to-severe psoriasis patients have a 5-year diminished life expectancy

Age, chronic stress, pollution exposure, alcohol intake, poor sleep, illness, and nutrient deficiencies all drain glutathione faster than the body can replenish it

The former is a process characterized by mitochondrial swelling, IMM permeabilization and OMM rupture as a secondary event